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Apoptosis is triggered rather than repair attempted when

  • A.the cell has just completed replication
  • B.the DNA damage is too extensive to mend
  • C.the cell has simply grown too large
  • D.a growth factor is present in excess

Answer: B

Removing a badly damaged cell protects the organism from the mutations it would otherwise pass on. p53 makes this decision, arresting the cycle first and choosing death only if repair fails. The choice between arrest and death is one of the most consequential a cell makes.

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