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The proteasome contributes to cell cycle control by

  • A.copying the DNA during S phase
  • B.attaching kinetochores to the chromosomes
  • C.destroying regulatory proteins at set moments
  • D.synthesising the cyclins as they are required

Answer: C

Abrupt destruction of cyclins and of the proteins holding sister chromatids together makes each transition sharp and irreversible. Regulation by degradation is what gives the cycle its one-way character. Synthesis and destruction together produce the oscillation.

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