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One of the signalling molecules used for bacterial cell-cell communication are :

  • A.N-acetyl hydroxy laccase
  • B.N-acyl homoserine laccase
  • C.N-acetyl homoserine lactone
  • D.N-acyl homoserine lactone

Answer: D

The bacterial signalling molecule is N-acyl homoserine lactone.

Gram-negative bacteria such as Vibrio fischeri and Pseudomonas aeruginosa use acyl homoserine lactones (AHLs) for quorum sensing. A LuxI-type synthase makes the AHL, which diffuses across membranes; when the population is dense enough, the AHL reaches a threshold, binds a LuxR-type regulator, and switches on genes for bioluminescence, virulence or biofilm formation.

The other names are distortions of the real one. A laccase is a copper-containing oxidase, not a signal, so both 'laccase' options are wrong; and the acyl chain, not an acetyl group, is the variable part that gives each species its own signal, which rules out 'N-acetyl homoserine lactone'.

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