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Assertion (A): A cancer cell may produce the very growth factor it responds to.
Reason (R): Autocrine signalling frees a cell from depending on signals made by other cells.

  • A.Both A and R are true, but R is not the correct explanation of A
  • B.A is true but R is false
  • C.A is false but R is true
  • D.Both A and R are true, and R is the correct explanation of A

Answer: D

Both are true and the reason gives the advantage to the tumour: self-sufficiency in growth signalling is one of the recognised hallmarks of cancer, and autocrine loops are one route to it. Independence from external growth signals is what the loop buys.

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