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If roughly one third of all approved drugs act on G protein-coupled receptors and there are about 900 approved drugs in a class, how many would that be?

  • A.about 450
  • B.about 30
  • C.about 300
  • D.about 90

Answer: C

A third of 900 is 300. The proportion illustrates how central this one receptor family is to pharmacology, and why so much effort goes into understanding it. Their structures were long difficult to determine, which slowed drug design.

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