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Inositol trisphosphate acts by

  • A.opening ion channels in the outer nuclear membrane
  • B.releasing calcium from the endoplasmic reticulum
  • C.phosphorylating various target proteins in the cytosol
  • D.binding directly onto the DNA within the cell nucleus

Answer: B

Produced when a membrane lipid is cleaved, it diffuses to the reticulum and opens calcium channels there. The other product of that cleavage, diacylglycerol, stays in the membrane and activates protein kinase C. One cleavage event thus produces two distinct signals at once.

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