Discussion
A receptor's specificity for its signal molecule depends chiefly on
Answer: A
Correct answer: the shape of its binding site
Specificity is molecular complementarity: the binding site’s shape and its distribution of charge and hydrogen-bonding groups fit one molecule and not others. That is why a cell is deaf to every signal for which it lacks a receptor, however concentrated, and why a drug designed to fit the same site can mimic or block the natural ligand.
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