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Scaffold proteins in signalling pathways serve to

  • A.destroy the signal molecule once it has acted
  • B.carry the signal across the plasma membrane
  • C.supply all the ATP that the cascade requires
  • D.hold successive components close together

Answer: D

Correct answer: hold successive components close together

A scaffold binds several members of a cascade at once, holding them in proximity so the signal passes efficiently from one to the next. It also prevents cross-talk, since components tied to one scaffold do not stray into a parallel pathway using the same kinases - which is how a cell runs several pathways through shared components without confusing them.

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