Discussion
Assertion (A): Many animal cells die if removed from their tissue and deprived of signals.
Reason (R): Their survival depends on continual signalling from neighbouring cells.
Answer: D
Correct answer: Both A and R are true, and R is the correct explanation of A
Both are true and the reason explains the phenomenon. Animal cells require continuous survival signals from their neighbours and their matrix, and in their absence the default programme of apoptosis proceeds. It is a control mechanism rather than a frailty: a cell that has strayed from its proper tissue dies, which is one of the barriers a metastasising cancer cell must overcome.
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