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State whether the following is true or false.
Mutations that make a signalling protein permanently active can cause cancer.

  • A.True only at large scales
  • B.False only at small scales
  • C.True
  • D.False

Answer: C

A component locked in its on state drives division whether or not a growth signal has arrived. The Ras protein is the classic case, and mutations in it are found in a large fraction of tumours. Roughly a quarter of all human cancers carry a Ras mutation.

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