Discussion
Compared with an endocrine signal, a signal passing through a gap junction is limited to
Answer: D
Correct answer: cells in direct physical contact
A gap junction is a channel joining the cytoplasms of two adjacent cells, so ions and small molecules pass only between cells that touch. That makes it the shortest-range signalling there is, and the fastest - which is why it synchronises the contraction of cardiac and smooth muscle, where the coupling must be essentially instantaneous.
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