Discussion
Upon stimulation of a eukaryotic cell, the intracellular calcium (Ca2+) is released from
Answer: A
The calcium is released from the Endoplasmic reticulum.
When a cell is stimulated through receptors coupled to phospholipase C, the second messenger inositol 1,4,5-trisphosphate (IP3) binds IP3 receptors, which are calcium channels in the ER membrane. The ER (the sarcoplasmic reticulum in muscle) is the main intracellular calcium store, so opening these channels raises cytosolic Ca2+ within seconds.
Mitochondria take up calcium and can buffer it, but they are not the store released on stimulation. The nucleus and peroxisomes are not calcium-release stores in signalling.
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