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The following statements are true regarding Clostridium perfringens except:

  • A.It is the commonest cause of gas gangrene
  • B.It is normally present in human feces
  • C.The principal toxin of C. perfringens is the alpha-toxin
  • D.Gas gangrene producing strains of C. perfringens produce heat resistant spores

Answer: D

Correct answer: Gas gangrene producing strains of C. perfringens produce heat resistant spores

This is the exception. It is the food poisoning strains of type A whose spores are heat resistant, surviving cooking to germinate as the food cools; the gas gangrene strains produce heat-sensitive spores. The other three statements are true: C. perfringens is much the commonest cause of gas gangrene, it is a normal inhabitant of the human intestine, and its principal toxin is the alpha toxin, a lecithinase.

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