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Which hormone stimulates HCL secretion?

  • A.Somatostatin
  • B.Gastrin
  • C.Secretin
  • D.Cholecystokinin

Answer: B

The hormone that stimulates HCl secretion is gastrin.

Gastrin is released by G cells in the antrum of the stomach when food, especially protein, enters it. It stimulates the parietal cells to secrete hydrochloric acid, both directly and by releasing histamine from nearby cells.

Somatostatin inhibits acid secretion. Secretin also inhibits gastric acid, and stimulates bicarbonate-rich pancreatic juice to neutralise acid entering the duodenum. Cholecystokinin causes gallbladder contraction and pancreatic enzyme secretion, and slows gastric emptying.

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