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During replication, Okazaki fragments elongate

  • A.leading strand towards the replication fork
  • B.lagging strand towards the replication fork
  • C.leading strand away from the replication fork
  • D.lagging strand away from the replication fork

Answer: D

Correct answer: lagging strand away from the replication fork

DNA polymerase can only add nucleotides to a 3’ end, so it works 5’→3’. On the lagging strand that direction is opposite to the way the fork is moving, so each Okazaki fragment is begun near the fork and extended away from it, until it meets the fragment made before. The leading strand, by contrast, is made continuously towards the fork.

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