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DNA replication is

  • A.conservative
  • B.conservative and discontinuous
  • C.semi-conservative and discontinuous
  • D.semi-conservative and semi-discontinuous

Answer: D

Correct answer: semi-conservative and semi-discontinuous

Two separate descriptions. Semi-conservative: each daughter duplex keeps one parental strand and one new one, as Meselson and Stahl showed. Semi-discontinuous: because synthesis is 5’→3’ only, one strand is made continuously (the leading strand) while the other is made in short Okazaki fragments (the lagging strand). Only one of the two is discontinuous, which is why it is semi-discontinuous.

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