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DNA unwinding is done by ____________

  • A.Ligase
  • B.Helicase
  • C.Topoisomerase
  • D.Hexonuclease

Answer: B

Correct answer: Helicase

Helicase uses the energy of ATP to break the hydrogen bonds between the paired bases and travel along the duplex, separating the two strands so each can be copied. Single-strand binding proteins then keep them apart, and topoisomerases handle the supercoiling that results.

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