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Name the protein, which is responsible for the formation of RNA primer?

  • A.Topoisomerase
  • B.Gyrase
  • C.Helicase
  • D.Primase

Answer: D

Correct answer: Primase

DNA polymerase cannot start a chain, only extend one, so every new strand needs a starter with a free 3’-OH. Primase, an RNA polymerase, lays down a short RNA primer - once on the leading strand and once for each Okazaki fragment. The primers are later removed and replaced with DNA.

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