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Telomeres are usually rich in which nucleotide?

  • A.Adenine
  • B.Guanine
  • C.Thymine
  • D.Cytosine

Answer: B

Correct answer: Guanine

Telomeric repeats are G-rich on the strand running 5’→3’ towards the chromosome end - TTAGGG in vertebrates. The guanine runs let the single-stranded overhang fold into a G-quadruplex, which is part of how the end is protected from being read as a double-strand break.

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