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A cesium chloride will separate DNA molecules by

  • A.absorption
  • B.resorption
  • C.density
  • D.adhesion

Answer: C

Correct answer: density

Caesium chloride spun at high speed forms a density gradient, and each DNA molecule settles where the solution’s density equals its own. This is what let Meselson and Stahl distinguish 15N-heavy, hybrid and light DNA, and what separates plasmid from chromosomal DNA in a classical preparation.

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