Discussion
The nicks or gaps between Okazaki fragments are eventually sealed by
Answer: B
Correct answer: DNA ligase
Once the RNA primer of each Okazaki fragment has been removed and the gap filled by polymerase, one phosphodiester bond is still missing. DNA ligase forms it, joining the fragments into a continuous strand. Gyrase manages supercoiling and polymerase extends chains; neither can close a nick.
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