Discussion
In a typical electrophoresis experiment, larger fragments of DNA move more
Answer: A
Correct answer: slowly, so they appear nearer the top of a gel photograph
The gel is a mesh, and a larger fragment threads through it more slowly. Since the samples are loaded at the top and run towards the anode below, the large fragments are left behind near the wells at the top, while small ones run furthest down. That is why a size ladder reads large-to-small from top to bottom.
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