Discussion
DNA polymerase I also has
Answer: B
Correct answer: both (a) and (b)
Pol I is unusual in carrying both exonuclease activities. The 3’→5’ activity proofreads, backing up over a mispaired base; the 5’→3’ activity chews forwards, which is what removes RNA primers and makes nick translation possible. Pol II and Pol III have only the proofreading one.
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