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Which of the following species lack a 'classical' histone H1?

  • A.Saccharomyces cerevisiae
  • B.Strongylocentrotus purpuratus
  • C.Xenopus laevis
  • D.Arabidopsis thaliana

Answer: A

Correct answer: Saccharomyces cerevisiae

Budding yeast has no classical linker histone. Its nucleosomes are packed with unusually short linkers and its genome is small, so it manages without one - it carries only the distantly related Hho1p, which does not behave like H1. Sea urchin, Xenopus and Arabidopsis all have conventional H1 variants.

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