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Carbon monoxide is toxic principally because it

  • A.Binds haemoglobin far better than oxygen
  • B.Irritates the lining of the airways
  • C.Dissolves in the blood to form an acid
  • D.Damages the alveolar membrane directly

Answer: A

Its affinity for haemoglobin is more than two hundred times that of oxygen, so even small concentrations occupy a large share of the binding sites. The blood carries less oxygen while appearing outwardly normal, which is what makes the gas so insidious.

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