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Carboxyhaemoglobin saturation is the measure of

  • A.The oxygen content of the lungs
  • B.Haemoglobin bound to carbon monoxide
  • C.The concentration of carbon monoxide in air
  • D.The rate at which carbon monoxide is exhaled

Answer: B

Correct answer: Haemoglobin bound to carbon monoxide

Carboxyhaemoglobin saturation is the percentage of the blood's haemoglobin that is bound to carbon monoxide rather than to oxygen. It is the standard measure of internal dose, because it reflects what has actually reached the bloodstream rather than what was present in the air.

Carbon monoxide binds haemoglobin some 200 to 250 times more strongly than oxygen does, so even a few parts per million in air produce a measurable saturation. The result is reduced oxygen carriage, felt first as headache and impaired judgement, and dangerous at higher levels.

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