Discussion
Which one of the following is not a peptide hormone?
Answer: C
The hormone that is not a peptide is T4 (thyroxine).
Thyroxine is an iodinated derivative of the amino acid tyrosine, an amine hormone, not a chain of amino acids. It is fat-soluble enough to enter cells and acts on nuclear receptors.
GnRH (a decapeptide), FSH (a glycoprotein) and CCK (a gut peptide) are all made of amino-acid chains, so they are peptide or protein hormones.
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