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Rough endoplasmic reticulum is distinguished from smooth by the presence of

  • A.ribosomes bound to its outer surface
  • B.enzymes for the synthesis of lipids
  • C.a connection to the plasma membrane
  • D.an internal store of calcium ions

Answer: A

Correct answer: ribosomes bound to its outer surface

The ribosomes are what make it rough, and they are there because the proteins they are making carry a signal sequence directing the whole complex to the membrane. Lipid synthesis, calcium storage and detoxification are functions of the *smooth* reticulum, so a cell’s balance between the two forms tells you what it does - a plasma cell is packed with rough, a steroid-secreting cell with smooth.

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