Discussion
Consider the following statements about vesicle traffic.
1. COPII vesicles carry cargo from the reticulum to the Golgi.
2. COPI vesicles carry material in the retrograde direction.
3. Clathrin coats every vesicle in the secretory pathway.
Answer: C
The first two are correct. The third overstates clathrin's role, which is confined chiefly to endocytosis and to traffic leaving the trans Golgi network. COPI and COPII handle the traffic between reticulum and Golgi instead.
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