Discussion
In the feedback regulation of an enzyme, the end product binds to the
Answer: B
The end product binds to the allosteric site of the enzyme.
In feedback inhibition, the final product of a pathway inhibits an enzyme near the start of the pathway. The product usually looks nothing like that enzyme's substrate, so it binds to a separate regulatory site, the allosteric site, and changes the enzyme's shape to lower its activity. An example is isoleucine inhibiting threonine deaminase.
Binding at the active site would be competitive inhibition by a substrate look-alike. The end product does not bind the enzyme-substrate complex or the substrate itself.
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