Discussion
Which of the following enzymes catalyses the reaction that introduces reduced nitrogen into cellular metabolism?
Answer: A
Correct answer: Bacterial glutamine synthase
Glutamine synthetase is the point at which ammonia enters organic combination, being attached to glutamate to make glutamine. From there the nitrogen passes to every other nitrogenous compound the cell makes, which is why the enzyme is among the most elaborately regulated known - by cumulative feedback from nine end products and by adenylylation.
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