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Which of the following is false?

  • A.Allosteric modulators may be inhibitory or stimulatory
  • B.Based on the nature of modulator, allosteric enzymes are of two types
  • C.Homotropic allosteric enzymes have the substrate and modulator same
  • D.Heterotropic allosteric enzymes have the substrate and modulator same

Answer: D

Correct answer: Heterotropic allosteric enzymes have the substrate and modulator same

That is the wrong way round. In a homotropic enzyme the substrate is itself the modulator - which is what produces cooperative binding and the sigmoid curve. In a heterotropic enzyme the modulator is a different molecule, typically the end product of the pathway.

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