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Discussion

Lock and Key model is also known as

  • A.Template model 
  • B.Induced fit model
  • C.Koshland’s model
  • D.Enzyme-substrate interaction model 

Answer: A

Correct answer: Template model

The lock and key model, proposed by Emil Fischer in 1894, is also called the template model: the active site is a rigid shape into which only the right substrate fits. Koshland’s induced fit model succeeded it, allowing the site to change shape as the substrate binds - which explains a good deal that a rigid template cannot.

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