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Hypoproteinaemia produces oedema by

  • A. Increasing hydrostatic pressure at capillary arteriolar end
  • B.Increasing interstitial fluid osmotic pressure
  • C.Decreasing colloidal osmotic pressure across the capillary wall
  • D.All of the above

Answer: C

Correct answer: Decreasing colloidal osmotic pressure across the capillary wall

Plasma proteins, albumin especially, hold water in the capillary by colloid osmotic (oncotic) pressure, which opposes the hydrostatic pressure driving fluid out. If the protein concentration falls - through starvation, liver failure or protein loss in the urine - that inward pull weakens, fluid accumulates in the tissues, and oedema results.

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