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Histamine in fish is formed from

  • A.lysine
  • B.tryptophan
  • C.histidine
  • D.histone

Answer: C

Correct answer: histidine

Bacterial histidine decarboxylase removes the carboxyl group from free histidine to give histamine. The reaction requires the amino acid to be present in quantity, which is why only certain fish families are implicated - the enzyme cannot make histamine from a substrate the fish does not contain.

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