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Once histamine has formed in fish, it

  • A.is destroyed by freezing
  • B.is removed by washing
  • C.is not destroyed by cooking
  • D.is destroyed by cooking

Answer: C

Correct answer: is not destroyed by cooking

Histamine is a small, heat-stable molecule that survives cooking, canning, smoking and freezing entirely. This is what makes scombroid poisoning different from a bacterial infection: killing the organisms achieves nothing once the toxin is formed, so the only control is preventing its formation in the first place.

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