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Which of the following is a type of molecular mass spectrometry ?

  • A.ICP-MS
  • B.LM-MS
  • C.LC-MS
  • D.GD-MS

Answer: C

The molecular mass spectrometry technique is LC-MS.

Liquid chromatography-mass spectrometry separates compounds and ionises them gently (for example by electrospray), so it measures intact molecules and their fragments. It is widely used for drugs, poisons and metabolites.

ICP-MS (inductively coupled plasma) and GD-MS (glow discharge) are atomic or elemental methods: they break the sample down into atoms and measure elements and isotopes. Laser microprobe mass spectrometry is likewise used mainly for elemental analysis of small particles.

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