Discussion
Time-of-flight mass spectrometry operates in :
Answer: B
Time-of-flight mass spectrometry operates in pulse mode.
In a TOF analyser, ions are accelerated by the same voltage so that they all gain the same kinetic energy, and their mass is found from the time they take to cross a field-free flight tube: lighter ions arrive first. For the timing to be meaningful all ions must start together, so they are produced or extracted in short pulses, for example by a pulsed laser in MALDI or by orthogonal pulsed extraction.
A continuous beam would give no start time, and 'direct' and 'syntactic' are not operating modes of a TOF instrument.
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