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The MRM is a technique in mass spectrometer stands for :

  • A.Multiple reaction monitoring
  • B.Multiple range monitoring
  • C.Multiple ratio monitoring
  • D.Magnetic resonance monitoring

Answer: A

MRM stands for multiple reaction monitoring.

In tandem mass spectrometry with a triple quadrupole, the first quadrupole selects a precursor ion, the second fragments it by collision, and the third selects a specific product ion. Monitoring several such precursor-to-product transitions at once is multiple reaction monitoring.

Because each transition is specific to a compound, MRM gives very sensitive and selective quantitation, and it is widely used in forensic toxicology to confirm drugs and poisons in blood and urine. 'Multiple range', 'multiple ratio' and 'magnetic resonance' monitoring are not what the term means.

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