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FUT3 gene name belongs to which of the following blood group system ?

  • A.Lewis
  • B.Kell
  • C.Duffy
  • D.MNS

Answer: A

FUT3 belongs to the Lewis blood group system.

The FUT3 gene encodes a fucosyltransferase (the Lewis enzyme) that adds fucose to precursor chains, producing the Lea and Leb antigens. The antigens are made in secretions and adsorbed onto red cells from plasma, which is unusual among blood groups.

The other systems have different genes: Kell is encoded by KEL, Duffy by ACKR1 (formerly DARC), and MNS by GYPA and GYPB.

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