Discussion
How many antigens are present in Diego blood group system ?
Answer: D
The Diego system has 21 antigens, according to the figure the key uses.
The Diego system (ISBT symbol DI, system number 010) is carried on band 3, the red-cell anion exchanger AE1 encoded by SLC4A1. It includes the high-incidence antigen Di(b) and the low-incidence Di(a), which is common in East Asian and South American Indigenous populations. Standard references such as the NCBI Blood Groups and Red Cell Antigens text count 21 antigens.
The ISBT list has grown since then, and recent reviews give 22 or 23, so the number depends on the year of the source. Of the options, 25 and 49 are too many and 02 is far too few, so 21 is the only one that matches the published figure.
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