Discussion
After removal of which of the following clear portion of the blood or plasma is called serum ?
Answer: D
Serum is the clear fluid left after removal of fibrinogen.
When blood clots, soluble fibrinogen is converted into a mesh of fibrin that traps the cells. The clot retracts and squeezes out a clear straw-coloured fluid: serum. Serum is therefore plasma minus fibrinogen and the other clotting factors used up in the clot.
Gamma globulins (antibodies) remain in serum, which is why serum is used to test for antibodies. Agglutinogens are the antigens on red cells and agglutinins are the antibodies in plasma; removing either does not turn plasma into serum.
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