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Synergism takes place when :

  • A.A person is addicted to drugs
  • B.A person takes more dose of drug to get the same effect
  • C.A drug is metabolized into two different substances
  • D.Two different drugs are taken at a same time and their effect is magnified.

Answer: D

Synergism takes place when two different drugs are taken at the same time and their effect is magnified.

In synergism the combined effect of two substances is greater than the sum of their separate effects, as when alcohol is taken with benzodiazepines or opioids and breathing is dangerously depressed. It is important in forensic toxicology when deaths occur at individually non-fatal levels.

Taking more of a drug for the same effect is tolerance, and being addicted is dependence. A drug being metabolised into two products is biotransformation, not synergism.

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