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By which method Nicotine is isolated from alkaline solution ?

  • A.Dry ashing
  • B.Wet digestion
  • C.Distillation
  • D.Sublimation

Answer: C

Nicotine is a volatile alkaloid, so when the biological material is made alkaline it can be separated by distillation (steam distillation) and collected in the distillate. Dry ashing and wet digestion destroy organic matter and are used for metallic poisons, and sublimation is used for compounds that pass from solid to vapour directly. Distillation is the method suited to nicotine from an alkaline solution.

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