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What is discrimination in an injector?

  • A.The split ratio varying between injections
  • B.Unequal transfer of compounds of differing volatility
  • C.The detector responding unequally to different compounds
  • D.The column retaining some compounds irreversibly

Answer: B

If the needle and liner do not vaporise every component equally, the less volatile ones are under-represented on the column and the composition reported is wrong. Detector response, irreversible retention and split variability are separate problems. Because discrimination distorts a quantitative result without distorting the chromatogram's appearance, it is detected only by comparing against a standard of known composition. Naming the cost of a choice alongside its benefit is what turns a fact into a design decision.

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