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What is a flame ionisation detector blind to?

  • A.Water and the permanent gases
  • B.Hydrocarbons of high molecular weight
  • C.Compounds containing halogens
  • D.Aromatic compounds with several rings

Answer: A

Substances with no carbon-hydrogen bonds to burn - water, carbon dioxide, nitrogen, the noble gases - produce essentially no ions and give no signal. Heavy hydrocarbons, halogenated compounds and aromatics all respond, some a little less per carbon. That a detector's blindness can be an advantage, letting a wet sample be injected without a solvent peak swamping the trace, is worth recognising alongside the limitation. Most errors here come from carrying a result across from a neighbouring case where it does not hold.

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