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Why is a chromatogram integrated rather than measured by hand?

  • A.Hand measurement cannot determine retention times
  • B.Integration identifies the compounds automatically
  • C.Hand measurement requires the peaks to be symmetrical
  • D.Integration is more reproducible and handles overlap

Answer: D

Software applies a consistent baseline and a consistent rule for splitting overlapping peaks, which two analysts measuring by hand would not. Retention times are readable either way, identification needs a standard or a spectrum, and symmetry helps but is not required manually. Removing operator judgement from a routine step is what makes results comparable between people and between days.

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