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What is the carrier gas required to be?

  • A.Highly soluble in the stationary phase
  • B.Reactive enough to derivatise the analytes
  • C.Denser than the compounds being separated
  • D.Inert towards sample and stationary phase

Answer: D

The carrier must move the sample without taking any part in the partition, so helium, nitrogen and hydrogen are used and oxygen is rigorously excluded. Solubility in the phase would destroy the separation, reactivity would change the analytes, and density is irrelevant. That the mobile phase contributes nothing chemically is the defining difference from liquid chromatography, where it contributes a great deal. Working one numerical case through both cases side by side fixes the distinction better than any rule of thumb.

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