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What is two-dimensional gas chromatography?

  • A.Two temperature programmes run in parallel
  • B.Two columns of different selectivity in series
  • C.Two detectors on one column at once
  • D.Two samples injected simultaneously

Answer: B

Fractions eluting from a first column are transferred in turn onto a second of quite different selectivity, so compounds unresolved on one are separated on the other. Two detectors, two samples and two programmes describe other arrangements. Multiplying the peak capacity by separating on two independent properties is what makes very complex mixtures such as petroleum tractable.

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