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In which organelle DNA, UGA codes for tryptophan ?

  • A.Chloroplast DNA
  • B.Mitochondrial DNA
  • C.Both mitochondrial and chloroplast DNA
  • D.Nuclear DNA

Answer: B

UGA codes for tryptophan in mitochondrial DNA.

In the standard genetic code UGA is a stop codon. Mitochondria of vertebrates, fungi and many other organisms use a variant code in which UGA is read as tryptophan, one of several mitochondrial departures from the universal code.

Chloroplasts use the standard code, so in chloroplast DNA UGA remains a stop codon; that rules out the chloroplast and 'both' options. In nuclear genes UGA is a stop codon, apart from its special use for selenocysteine in a few genes.

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